What makes this herb favorable is that while it is quite effective at activation circulation, it is also very cooling in nature, making it useful in cases of excess heat. Information tailored to you, updated every month. You must be logged before you can follow this page. All factual claims are Juglans nigra(Black walnut) 3. The whole flowering plant is used to make medicine. manufacturers, food companies, and industry funders. Our evidence-based analysis on japanese knotweed features At Examine.com, our incentives line up with yours — getting unbiased information. Polygonum Cuspidatum, Huzhang, Fleeceflower, Monkeyweed, itadori, Polygonum Japonicus, Kudzu, Polygonum Multiforum (different composition from a related plant), Pueraria lobata (also called Kudzu), (As a source of Resveratrol, it might be prudent to see what is synergistic with Resveratrol; by extension they are somewhat synergistic with Japanese Knotweed). Overview Information Knotweed is an herb. Japanese knotweed is an excellent source of resveratrol, the chemical compound found in grapesexcept Japanese knotweed contains high concentrations of trans-resveratrol, the active form of the compound most useful to the body. 2005. Our independent, unbiased approach reveals what works (and what's a waste of time and money). Effects of nattokinase on blood pressure: a randomized, controlled trial. Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy. Becoming a member also unlocks our study database of 400+ supplements and their effects on 600+ health outcomes. In traditional Chinese medicine formulations containing Hu Zhang are prescribed for treating cough, hepatitis, jaundice, amenorrhea, vaginal discharge, joint pain, burns, and snake bites. Japanese knotweed features an antioxidant called resveratrol. The team includes nutrition researchers, registered On Sunday the Philippines reported the first death outside of China. The dried root is used medicinally and is listed in the Pharmacopoeia of the People’s Republic of China. Taking it when you are on estrogen replacement therapy or birth control pills might impact the effects of these drugs. All factual claims are followed by specifically-applicable references. The root is used as medicine. This page is regularly updated, to include the most recently available clinical trial evidence. cinnamon). Identifying Japanese Knotweed . Once you know that it’s edible, I hope that you’ll look at this plant with a new perspective. Although used for various applications, few clinical studies validate claims and guidance regarding dosing or safety is limited. As yet there is no widely agreed upon dosage range – further research is needed. followed by specifically-applicable references. In traditional Chinese medicine, BioPure Japanese Knotweed is described as bitter and slightly cold, and its uses include supporting the body’s natural detoxification pathways, increasing blood circulation, clearing heat, for various skin concerns, menstruation support, improving liver and cardiovascular health, and as a diuretic. Japanese Knotweed, or Polygonum Cuspidatum, is a Traditional Chinese Medicine used for circulation and heart health. All rights reserved. Reviewed by Russell Greenfield, M.D., August, 2016. Each member of our research team is required to have no conflicts of interest, including with supplement The only current human study used Japanese Knotweed at 200mg daily and standardized to 40mg Resveratrol which was effective. If undergoing medical therapies, then consult with your respective Therapist or Health Care Professional about possible interactions between your Treatment, any Pharmaceuticals or Drugs being given, and possible nutritional supplements or practices hosted on Examine.com. It also appears to have neuroprotective and antimicrobial activity. Japanese Knotweed Chinese medicine is also a very effective pain reliever, and clears dampness and heat. ... are also studying the potential use of a plant commonly known as Japanese knotweed … Become an Examine.com member to get access to the latest research. Many may associate resveratrol with wine, however, trans -resveratrol is commonly derived from Japanese knotweed for use in dietary supplements. Japanese knotweed in a herbaceous perennial that in native to Japan, North China, Taiwan and Korea 1.According to Whole Foods Magazine Online, Japanese knotweed contains significant concentrations of the potent antioxidant resveratrol 1.Resveratrol occurs naturally in many foods such as grapes, peanuts, mulberries and red wine in addition to Japanese knotweed 1. And my second question: is a common infusion also a good way for resveratrol extraction from japanese knot weed… Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect. Examine.com and its Editors do not advocate nutritional supplementation over proper medical advice or treatment and this sentiment will never be expressed through pages hosted under Examine.com. In traditional Chinese medicine, Japanese Knotweed is described as bitter and slightly cold, and its uses include supporting the body’s natural detoxification pathways, increasing blood circulation, clearing heat, for various skin concerns, menstruation support, improving liver and cardiovascular health, and as a … A broadly systemic plant, Japanese Knotweed Root modulates and enhances immune function, is anti-inflammatory for both arthritic and bacterial inflammations, protects the body against endotoxin damage, and is a potently strong angiogenesis modulator, highly protective of the endothelia of the body. There are dozens of ways to eat Japanese knotweed, and I’ve included links to … Hu Zhang may have estrogenic effects. Cinnamomum, i.e. Studies indicate the most beneficial use to be in pancreatic, breast, and ovarian cancers. That's why we don’t sell any advertising or supplements. Stay Connected With Dr. Weil - Get Free Newsletters Right In Your Inbox, Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. or Healthy Lifestyle Brands. Hu Zhang ( Polygonum cuspidatum) is the Chinese name for a plant also known as Japanese knotweed and Mexican bamboo. Japanese knotweed also contains vitamins and minerals and has been used in traditional medicine for centuries. Japanese knotweed shoots are rich in vitamin A, resveratrol, zinc, manganese, potassium, and vitamin C. Most supplements called ‘resveratrol’ (a powerful antioxidant) are now made with Japanese knotweed. We have a strict editorial process. The dried root is used medicinally and is listed in the Pharmacopoeia of the People’s Republic of China. Hu Zhang is used medicinally to treat atherosclerosis (hardening of the arteries), heart disease, and high cholesterol, as well as constipation, hepatitis, and gallstones. Resveratrol can also slow blood clotting, which could increase the effects of drugs such as aspirin, clopidogrel (Plavix), and warfarin (Coumadin) that slow blood clotting. Japanese Knotweed (Polygonum cuspidatum) Japanese knotweed has been in the armament of Chinese and Japanese herbal traditions for thousands of years. Hu Zhang is … Kim JY, Gum SN, Paik JK, Lim HH, Kim KC, Ogasawara K, Inoue K, Park S, Jang Y, Lee JH. Bonus: unlock the supplement Human Effect Matrix and all health topics on Examine.com. Examine.com does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses supplements. Even though it has been used for centuries in traditional Chinese medicine, further research is needed to better assess safety, effectiveness, and appropriate dosing. is a traditional medicinal herb with significant effects; dating back more than 1800 years, it is widely used in Asia. Most research on Japanese Knotweed has been pertaining to either suppressing its invasive tendencies, or controlling it to become a large scale producer of Resveratrol for medical or supplemental usage. The safety of Hu Zhang during pregnancy, breastfeeding, and childhood has not been established. You are now following Japanese Knotweed. I have found a japanese knotweed “tea” in a store,but this one is made from leaves and stems.Do these plant parts contain enought resveratrol for preparation of a tincture? Japanese knotweed is quickly becoming the preferred source of resveratrol. HIGH or Polygonum cuspidatum contains a compound known as polydatin, or piceid. In a study published in the journal BMC Complementary and Alternative Medicine , researchers from Guangzhou University of Chinese Medicine in China investigated the bioactivity of Japanese knotweed against hepatocellular carcinoma (HCC). Hu Zhang is also used as folk medicine in Japan and Korea. Japanese Knotweed has on your body, how much evidence 55 unique references to scientific papers. each outcome. to see the full set of research information and references for Japanese Knotweed. 55 unique references to scientific papers. We are 100% backed by science. "Japanese Knotweed," Examine.com, published on 30 September 2013, last updated on Yes! Therapeutic Uses, Benefits and Claims of Chinese Knotweed (Fo-Ti) Chinese Knotweed (Polygonum multiflorum) – ©The Herbal Resource Fo-ti is one of principal ingredients of the “Shou Wu Chih,” which is one of the Chinese patent medicines. Herbal Information on Organic Japanese Bushy Knotweed Rhizome in Bulk Powder Form. Because some evidence suggests that Hu Zhang has estrogenic effects, it might worsen hormone-sensitive cancers (breast, uterine, ovarian) and promote endometriosis or uterine fibroids, both of which are estrogen-sensitive. Scientific research does not always agree. Common Names: Bushy Knotweed, Japanese Bushy Knotweed, Tiger Cane, Giant Knotweed, Some people may refer to this herb as Japanese Bushy Knotweed Root and Rhizome Botanical Name: Polygonum cuspidatum; Rhizome Pin Yin Name: Hu Zhang Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more. 14 June 2018, It’s also medicinal, but more on that later. Hu Zhang contains resveratrol, an antioxidant found in red wine and in the skin of grapes that might slow the speed at which the liver breaks down some medications. You will be notified when any significant update is made. Because Hu Zhang contains resveratrol, a compound that may possess growth factor-inhibiting actions, this agent should not be given to children. The first Japanese knotweed removal firm I approached wanted to charge me thousands of pounds to excavate the area without checking first if the plant was even alive, which seemed ridiculous. According to the Natural Medicines Comprehensive Database there isn’t enough known about Hu Zhang to determine its effectiveness as a treatment for these disorders. Other Uses: Farm Fertility On our farm, we take the plants that grow rampantly and prolifically very seriously. Make informed decisions about your health, https://examine.com/supplements/japanese-knotweed/, Robust research conducted with repeated double-blind clinical trials, Multiple studies where at least two are double-blind and placebo controlled, Single double-blind study or multiple cohort studies, Uncontrolled or observational studies only. Resveratrol and the whole herb support normal immune function and offer anti-inflammatory and anticancer properties. “Because patients are currently turning to herbal remedies to fill the treatment gaps left by antibiotics, this research is a critical step in helping clinicians, as well as patients, understand which ones may offer the most potential benefit.” According to this study, carried out by Prof. Ying Zhang’s group at the Johns Hopkins Bloomberg School of Public Health, the seven herbal medicines that have the ability to kill B. burgdorferiin test tubes are: 1. Japanese knotweed is a member of the buckwheat family. Traditional Chinese medicine, herbs from the rain forest, South American herbs, Traditional Native American herbs, etc. Japanese knotweed belongs to the Fallopia genus and Polygonaceae family. Hu zhang is the Chinese name given to a plant with the scientific name of Polygonum cuspidatum. www.drweil.com, Feeling Stressed Out? Natural Medicines Comprehensive Database, http://naturaldatabaseconsumer.therapeuticresearch.com/nd/Search.aspx?rn=3&cs=NONMP&s=NDC&pt=100&id=1111&fs=NDC&searchid=45838311, accessed march 30. Specific for this are Glycyrrhiza spp (licorice), Scutellaria baicalensis (Chinese skullcap root), Sambucus spp (elder), luteolin, Aesculus hippocastanum (horse chestnut), 13 Polygonum cuspidatum (Japanese knotweed root), Rheum officinale, and plants high in procyanidins and lectins (e.g. Polygonum c… Hu Zhang. VERY HIGH means that most of the scientific research agrees. Along with ginger, holy basil, turmeric, green tea, and rosemary, Hu Zhang has naturally occurring anti-inflammatory compounds that act as COX-2 inhibitors (the COX-2 enzyme promotes pain, swelling, and inflammation; inhibitors selectively block that enzyme). Leonurus japonicusHoutt. We have a strict editorial process. Huan Zhang et al, “A Review of the Pharmocological Effects of the dried root of Polygonum cuspidatum (Hu Zhang) and its Constituents”, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806114/, accessed March 30, 2014A Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its Constituents, A Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its Constituents, Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its Constituents. ANTI-INFLAMMATORY - Resveratrol is a known anti-inflammatory and antioxidant. It is also well known as an herbal support for … Reproduction in whole or in part without permission is prohibited. Most of the effects of Japanese Knotweed can be traced back to either the stilbenes (resveratrol) or the anthraquinones (emodin) for the circulatory and gastrointestinal help, respectively. For information specific to the activity of resveratrol, see … The plant arrived from Japan to the U.K. and then to North America in the 19th century as a landscaping ornamental. Become an Examine Personalized member to access the latest nutrition research on over 400 supplements across more than 600 different health goals, outcomes, conditions, and more. It is a very good source of resveratrol, and most benefits of Japanese Knotweed may actually just be benefits of Resveratrol. Composition analysis of Japanese Knotweed reveals it to be a vessel for Resveratrol (as well as a few other compounds structurally similar to resveratrol and may act in the same way) and anthraquinone compounds that possess slight laxative effects; like Senna root but less potent. Traditional Chinese Medicine (TCM) is an ancient form of healthcare that dates back over 2,500 years and includes natural treatments such as acupuncture, herbal remedies, dietary advice, stress/emotional support, exercise including tai chi and qi gong and treatments such as cupping and moxibustion.TCM along with Ayurveda two of the oldest and most renowned forms of ancient medicine … (December 17, 2009). Examine.com is intended to be used for educational and information purposes only. According to a review published in September 2013 in the journal Evidence Based Complementary and Alternative Medicine, pharmacological and clinical studies suggest that Hu Zhang has antiviral, antimicrobial, anti-inflammatory, neuroprotective, and cardio-protective functions. The Human Effect Matrix summarizes human studies to tell you what effects Click here   It prefers sunny, moist areas, including riverbanks, roadsides, lawns, and gardens. Although there are other bioactives in Japanese Knotweed, it may be prudent to dose it in accordance to the dosing guidelines on the resveratrol page. Huzhang (Japanese Knotweed) has been used in traditional Chinese medicine as well as in Japan and Korea for many years. To use Japanese Knotweed Root tincture for cancer treatment, you will need to work with a healthcare professional to determine a dosage relevant to your treatment plan. Some studies have used extracts standardized to 20% trans-resveratrol. Some studies have suggested that resveratrol may have anticancer properties, and may protect heart and brain health. dietitians, physicians, and pharmacists. which have been used safely for thousands of years. for this page. Japanese knotweed is edible, and it’s tasty. In China, it is believed that the medication prepared from this plant rejuvenate the body. Our free five day mini-course on supplements teaches you what works, what doesn't work, and what to look out for when buying supplements for yourself. Most of the effects of Japanese Knotweed can be traced back to either the stilbenes (resveratrol) or the anthraquinones (emodin) for the circulatory and gastrointestinal help, respectively. Its scientific names include Fallopia japonica and Polygonum cuspidatum. 6 Ways To Fix That, ASAP. This plant is an invasive species yet has been used traditionally in Chinese and Japanese medicine for its benefits on gastrointestinal health and circulatory health (among some other claims such as cancer prevention). Japonicus is the species of plant most commonly referred to as Japanese Knotweed. HighBeam Research. You should not use the information on this website for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. Limited trials have been conducted in humans, but it appears to have similar effects to resveratrol due to the resveratrol content. Cryptolepis sanguinolenta 2. Researchers at the state-run academy, a top government think tank, are also studying the potential use of a plant commonly known as Japanese knotweed to alleviate symptoms. Knotweed rhizomes and young sprouts are used in a traditional Asian medicine as laxatives, and occasionally as foods. Japanese knotweed, an Asian traditional medicine, contains polyphenol resveratrol which is found to have anti-tumour and anti-inflammatory effects and protects the nervous system and heart. Get our free 5-day course on the essentials of supplementation. Suggested dosage: 200-800 mg Japanese knotweed (standardized to 50% trans-resveratrol) two to three times daily. Japanese Knotweed Supreme contains trans-resveratrol, the form best absorbed by the body. The study in question measured nF-kB activity and noted a 25% decrease, which is somewhat novel (not a common measurement) and to quite a large degree; may be related to the, Appears to reduce oxidative biomarkers, requires more evidence to gauge potency and reliability thereof, A decrease in TNF-a has been noted following oral consumption of japanese knotweed, Blood glucose appears to be unaffected following ingestion of Japanese knotweed in otherwise healthy lean persons, No significant influence on HDL-C in otherwise healthy lean persons, No significant alterations in fasting insulin levels seen with treatment, Insulin sensitivity is unaffected in otherwise healthy lean persons given this supplement, LDL-C appears to be unaffected, but testing has not been conducted in metabolically unwell persons, No significant influence on leptin in otherwise healthy and lean individuals, No significant alterations in cholesterol seen with Japanese Knotweed ingestion, No significant influence of Japanese Knotweed on triglycerides. JKW has been used in traditional forms of Asian medicine for centuries and offers a high level of safety. Click here to see the full set of references This page features 55 references. Resveratrol in Japanese Knotweed inhibits cancer cells without harming the liver. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. Japanese knotweed (Polygonum cuspidatum) is, herbaceous perennial plant, native to eastern Asia in Japan, Korea and China.In traditional Chinese medicine (TCM), the plant is known as huzhang. During the 1800s, Polygonum cuspidatum was introduced to Europe and America as an ornamental plant. Traditional Chinese Medicine has used it as a blood­moving herb, to resolve inflammation, stagnation, and poor circulation and also as a supportive herb to counter debility and immune fatigue. there is, and how strong these effects are. Japanese knotweed has been used in Chinese medicine due to its therapeutic properties. This page features 55 references. Hu Zhang (Polygonum cuspidatum) is the Chinese name for a plant also known as Japanese knotweed and Mexican bamboo. If using any pharmaceuticals or drugs given to you by a doctor or received with a prescription, you must consult with the doctor in question or an equally qualified Health Care Professional prior to using any nutritional supplementation. Polygonum Cuspidatum var. Chinese Herb: Hu Zhang (Japanese Knotweed) Meaning "Tigers Cane," Hu Zhang is an herb within the Blood Invigorator category. “Nattokinase, the “Japanese wonder” gets your blood pumping.” Townsend Letter for Doctors and Patients. The direction and size of the supplement's impact on ©Copyright 2020 Healthy Lifestyle Brands, LLC. Since I was not familiar with Japanese Knotweed, I began to do some research and found that this herb is high in resveratrol, emodin, and is primarily used in Chinese medicine for circulation, heart, and GI health. https://examine.com/supplements/japanese-knotweed/, © 2011-2020 Examine.com Inc | Privacy | Terms of Service | Disclaimer | About Us | Contact Examine.com. Mat Day at Environet took a much more flexible approach and treated me like an individual customer. It has also been used to treat cancer, burns, osteomyelitis (infection of the bone), gout, menstrual pain, and menopausal symptoms including hot flashes. An employee wears a protective face mask at a traditional Chinese medicine store in Beijing on Saturday. In traditional Chinese medicine, it is essential in the treatment of menstrual and delivery disorders caused by blood stasis, such as dysmenorrhea, amenorrhea, and postpartum hemorrhage. Arm yourself with the knowledge you need to make the right decisions about your health. Any third party offering or advertising on this website does not constitute an endorsement by Andrew Weil, M.D. Examine.com and its Editors do not ensure that unforeseen side effects will not occur even at the proper dosages, and thereby does not assume liability for any side effects from supplements or practices hosted under the domain of Examine.com. 150+ studies summarized across 25 different categories every month. S also medicinal, but it appears to have similar effects to resveratrol due to its therapeutic.! Buckwheat family most recently available clinical trial evidence herbs from the rain forest South! To scientific papers blood pressure: a randomized, controlled trial with wine, however, -resveratrol! 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Whole herb support normal immune function and offer anti-inflammatory and anticancer properties hu Zhang is a... We don ’ t sell any advertising or supplements you must be logged before you can this! And anticancer properties, and most benefits of Japanese knotweed is quickly the... Many years brain health: Farm Fertility on our Farm, we take the that! Updated, to include the most beneficial use to be in pancreatic, breast, ovarian... Anti-Inflammatory - resveratrol is a known anti-inflammatory and anticancer properties to get access to the resveratrol content japonicus is species..., registered dietitians, physicians, and childhood has not been established 200mg daily and standardized to %. Roadsides, lawns, and does not assume liability if one misuses supplements knotweed rhizomes and young are... Medication prepared from this plant with a new perspective Pharmacopoeia of the supplement 's impact on each.. That you ’ ll look at this plant with a new perspective much more flexible approach and me... 55 unique references to scientific papers an employee wears a protective face mask at a traditional Chinese is... Different categories every month, Polygonum cuspidatum ) is the species of plant most commonly referred to as knotweed... Knotweed for use in dietary supplements, and childhood has not been established, 2016 Doctors Patients. Studies summarized across 25 different categories every month more than 1800 years, it is used! Chinese and Japanese herbal traditions for thousands of years not assume liability for any actions undertaken visiting. “ Nattokinase, the “ Japanese wonder ” gets your blood pumping. ” Townsend for! And most benefits of resveratrol with wine, however, trans -resveratrol is derived...